How long should I wait to sleep on a new hybrid mattress?

You can sleep on a new hybrid mattress after just 2 hours, though most manufacturers recommend waiting 24 hours for full expansion and off-gassing before regular use.

Hybrid mattresses combine foam comfort layers with an innerspring coil base. The foam layers need time to decompress fully after being compressed for shipping, and any off-gassing odor from the foam dissipates faster with ventilation during those first hours. Sleeping on a hybrid mattress too soon won't damage it, but the feel will be slightly firmer than its final state until the foam fully expands.

Minimum wait time before sleeping on a new hybrid mattress: 2 hours.
Full foam expansion in a hybrid mattress typically takes 24–72 hours.
Off-gassing odor in hybrid mattress foam layers usually dissipates within 24–48 hours with ventilation.
Hybrid mattress foam layers expand faster in a warm room (68–72°F) than in a cold one.
Sleeping on a hybrid mattress before full expansion does not void most manufacturer warranties.